Paediatric patients presenting with an acute acetaminophen overdose should be observed and treated for at least 48 hours after ingestion of the drug.
United States researchers report the presence of normal values for prothrombin time (PT), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) within 48 hours of ingestion is the best predictor of low hepatotoxicity risk in such children.
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