The dobutamine/atropine magnetic resonance imaging (MRI) stress test may be useful to forecast risk of myocardial infarction (MI), according to a report in an Oct. 14 rapid access publication of Circulation.
On this test, inducible ischemia or left ventricular (LV) ejection fraction (LVEF) of less than 40% was associated with risk of MI independent of arteriosclerosis risk factors. “Regional assessments of [LV] wall motion obtained during MRI cardiac stress tests can be used to identify myocardial injury and ischemia, but the utility of MRI stress test results for the assessment of cardiac prognosis is not known,” write W. Gregory Hundley, MD, and colleagues from Wake Forest University School of Medicine in Winston-Salem, North Carolina.
Dr. Hundley’s group performed dobutamine/atropine MRI stress testing for the detection of inducible ischemia on 279 patients referred because of poor LV endocardial visualization with echocardiography. During follow-up (average duration, 20 months), the investigators tabulated rates of MI, cardiac death, death from any cause, coronary arterial revascularization, and unstable angina or congestive heart failure requiring hospitalization.
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