NEW YORK (Reuters Health) Oct 02 –

Diabetic patients, especially those with related complications, exhibit sympathetic denervation in the pupil, according to a report in the September issue of Diabetes Care. The cocaine eye-drop test can be used to rapidly assess sympathetic denervation.

Dr. Hendrik Lehnert, of Otto-von-Guericke-Universit t Magdeburg, Germany, and colleagues examined sympathetic pupillary responses in 47 type 1 diabetics with and without long-term complications and in 20 healthy controls. Long-term complications were defined as cardiac autonomic neuropathy (CAN), peripheral sensomotor neuropathy, retinopathy, and nephropathy.

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