Intrathecal clonidine appears to be effective and tolerable in the long-term treatment of intractable chronic pain associated with cancer.
Clinicians who use clonidine for long-term intrathecal infusion should be aware, however, of the risk of severe rebound system hypertension if the regimen is abruptly halted, say researchers at MD Anderson Cancer Center, Houston, Texas, and Alabama Pain Center, Huntsville, Alabama, United States.
Epidural clonidine has previously been shown effective in treatment of neuropathic pain …
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