The formulation of some calcium carbonate supplements significantly interferes with calcium absorption and patients may thus be getting substantially less calcium than might be presumed based on product labeling.
Dr. Robert Heaney and Dr. Janet Barger-Lux from Creighton University, Omaha, retrospectively examined the net effect of inert ingredients such as excipients, sweeteners, flavorings and coatings, as well as manufacturing processes such as tableting, on the absorbability of calcium in eight different calcium carbonate supplements.
Each supplement was compared with plain calcium carbonate which, being pure, has the highest possible absorbability of any calcium carbonate formulation. According to test results presented during the 24th annual meeting of the American Society for Bone and Mineral Research, the team found that only two calcium carbonate supplements – both oral tablets, although one was chewable – had rates of absorbability that were comparable to plain calcium carbonate.
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