American Journal of Clinical Nutrition
04/01/2002
By Elda Hauschildt
Oxidative stress may play a role in the etiology of benign prostatic hyperplasia (BPH).
United States researchers say they observed modest direct associations between BPH and intakes of total energy, protein and long-chain polyunsaturated fatty acids in middle-aged and older men.
Specific long-chain polyunsaturated fatty acids — eicosapentaenoic (EPA), docosahexaenoic (DPA) and arachidonic — are the potential links to oxidative stress, say investigators from Harvard University and Brigham and Women's Hospital in Boston, Massachusetts and Johns Hopkins University in Baltimore, Maryland.
They found four direct associations. One association was total energy intake and total BPH and high-moderate to severe lower urinary tract symptoms. A second related total and animal protein intakes and total BPH and BPH surgery. A third associated EPA and DHA and total BPH and BPH surgery and enlarged prostate. A final association was between total polyunsaturated fats and all definitions of BPH.
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