In women with polycystic ovary syndrome (PCOS), treatment with the insulin-lowering drug metformin appears to reduce FSH-stimulated aromatase activity, according to a recent report. This finding lends support to the hypothesis that hyperinsulinemia plays a key role in the pathogenesis of PCOS.
Dr. Vincenzo De Leo, from the University of Siena in Italy, and colleagues assessed the effect of metformin therapy on FSH-stimulated aromatase activity in 20 women with PCOS. Their findings are published in the December issue of Fertility and Sterility.
תגובות רוצה להצטרף לדיון?
יש להתחבר כדי להגיב.
התחבראין תגובות עדיין. היה הראשון להגיב!