Hepatology
04/08/2002
By Veronica Rose
Even patients with advanced cirrhosis who have significant portal hypertension have some degree of hepatic arterial buffer response preserved, say investigators at the University of Munich, Munich, Germany and Albrecht-Ludwigs-University, Freiburg.
They describe HABR as an important compensatory mechanism designed to maintain liver perfusion by hepatic vasodilation on reduction of portal venous perfusion. However, this mechanism is believed to be impaired in patients with advanced cirrhosis.
Accordingly, the investigators tested the effects of a transjugular intrahepatic portosystemic shunt (TIPS) on HABR as reflected by alterations in the resistance index (R1) of the hepatic artery.






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