– More than 90% of drugs approved since 1980 have not been properly tested to rule out possible teratogenic effects, study findings show.
Animal testing is the first step to determine if a drug is a possible teratogen. After drug approval, careful follow-up studies are still needed to confirm the drug’s safety. However, Drs. J. M. Friedman and W. Y. Lo, from the University of British Columbia in Vancouver, Canada, found that for the vast majority of new drugs these follow-up studies have not been performed.
As such, more than 90% of new drugs are still considered to have an “undetermined” risk of producing birth defects, according to the report in the September issue of Obstetrics & Gynecology.
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