Early development of a restrictive pattern of ventricular filling in pregnant diabetics can lead to complications during delivery.
Whereas pregnancy in healthy women results in a reversible physiological left ventricular hypertrophy, a disturbed relaxation pattern and a temporary decrease of left ventricular systolic function, pregnant women who are diabetic have delayed relaxation at the beginning of pregnancy and develop a restrictive filling pattern, say specialists in Düsseldorf, Germany. They studied the course of haemodynamic parameters under the increased volume load during pregnancy and delivery in women with insulin-dependent diabetes. The specialists examined 51 women with insulin-dependent diabetes and 51 healthy pregnant women. Fifty one healthy women who were not pregnant were used as controls.
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