Angiotensin-converting enzyme inhibition for moderate to severe diabetic retinopathy is unlikely to help normotensive type 2 diabetic patients. A pilot study was stopped prematurely after a mean duration of 7.2 months because small doses of enalapril did not retard the progression of moderate to severe diabetic retinopathy.
Earlier reports had indicated that angiotensin-converting enzyme inhibitors might have a beneficial effect on mild diabetic retinopathy.





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