Autologous cell transplantion may benefit ischemic hearts and legs, according to three presentations on Nov. 18 at the American Heart Association’s 75th Scientific Sessions held in Chicago, Illinois. Two studies focused on injecting autologous bone marrow cells or autologous skeletal myoblasts into the scarred area of an infarcted heart. In another study, injecting autologous bone marrow into ischemic limbs led to new vessel growth, reducing the need for amputation.
“Bone marrow not only can differentiate into heart cells, but also smooth muscle cells, connective tissue cells and other types of cells to reconstitute the entire structure of a tissue,” presenter Manuel Galinanes, MD, from the University of Leicester in the U.K., says in a news release. “The benefit [of transplanting bone marrow into scar tissue of the heart] could be seen only six weeks after injection.”
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