The results of a 12-year prospective follow-up study show a strong relationship between the presence of islet antibodies at diagnosis of adult-onset diabetes and future beta-cell function.
This study argues for repeated islet antibody testing beginning at diagnosis in patients with adult-onset diabetes, Dr. Henrik Borg from Lund University, Malmo and Swedish colleagues write in the June issue of the journal Diabetes.
They previously found that a group of adult diabetics with islet cell antibodies had high levels of glutamic acid decarboxylase 65 antibodies (GADA) and/or IA-2 antibodies at diagnosis, and more severe beta-cell dysfunction 5 years after diagnosis, than diabetics with lower GADA levels.
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