Laurie Barclay, MD Oct. 10, 2002
Treatment with either opioids or tricyclic antidepressants (TCA) is effective in treating postherpetic neuralgia (PHN) without causing cognitive impairment, according to results of a double-blind, crossover-design trial published in the Oct. 8 issue of Neurology.
“By comparing opioids to antidepressants head to head, our study suggests that opiates effectively relieve pain and are preferred by a greater proportion of patients,” lead author Srinivasa N. Raja, MD, from Johns Hopkins University in Baltimore, Maryland, says in a news release. “This adds further evidence that opioids are a good alternative for patients not responding to other types of pain medications.”
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