NEW YORK (Reuters Health) Jun 18 –
The likelihood that an individual with an inherited susceptibility to melanoma will actually express the disease varies widely by geographic location, according to a report published in the June 19th issue of the Journal of the National Cancer Institute.
The most common cause of an inherited susceptibility to melanoma involves mutations in the CDKN2A gene. Approximately 20% of melanoma-prone families demonstrate such mutations, lead author Dr. D. Timothy Bishop, from St. James’s University Hospital in Leeds, UK, and colleagues note.
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