Resistant propionibacteria, widely distributed on acne-prone skin and in the nares, may be difficult to eradicate using existing treatments, say specialists in Leeds, England.
Although cutaneous propionibacteria were implicated in acne pathogenesis, the exact role in causing inflammation was unclear.
Also, there were few formal data on prevalence and distribution. Antibiotics and other agents which reduced the numbers of propionibacteria on skin were therapeutic but resistance in the target organism often developed.
The specialists monitored the prevalence of skin colonisation by antibiotic-resistant propionibacteria in 4,274 acne patients at a dermatology out-patient clinic over 10 years from 1991. They also examined the distribution of resistant strains on acne-prone skin and in the nares.
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