Increased elevated C-reactive protein accompanies progressive thyroid failure, possibly proving to be an additional risk factor for developing coronary heart disease in patients with hypothyroidism.
An association between hypothyroidism and premature atherosclerosis and cardiovascular disease was already known to exist. Now, following the recent emergence of C-reactive protein (CRP) and total homocysteine (tHcy) as additional cardiovascular risk factors, Swiss endocrinologists at University Hospitals in Basel investigated both values.
Initially, they investigated CRP and tHcy in varied severities of primary hypothyroidism a double -blind placebo-controlled trial. A second study evaluated L-thyroxine therapy effects on patients with subclinical hypothyroidism (SCH).
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