Special to DG News
PHILADELPHIA, PA — April 11, 2002 — Omega-3 fatty acids appear to be as beneficial for patients with newly transplanted hearts as they are for those with ailing and healthy native hearts.
The findings were presented here today at the 2002 Annual Session of the American College of Physicians-American Society of Internal Medicine.
William Harris, PhD, and colleagues from the University of Missouri Kansas City School of Medicine gave 25 stable heart transplant patients two capsules of omega-3 fatty acid daily – each capsule contained 500 mg of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). Standard drug therapy was unaltered.
Blood samples were collected at baseline and at six months. Serum cytokine levels were determined by enzyme-linked immunosorbent assay (ELISA). The researchers were able to analyse baseline and post-treatment cytokine levels in 17 patients. Five patients discontinued the study for reasons not related to the protocol, and baseline blood samples for three patients were lost in processing. A paired t test (two-tailed) was used to determine treatment effect.
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