Results of a study published in the October 20th issue of the International Journal of Cancer suggest an association between elevated circulatory insulin-like growth factor (IGF)-1 levels and an increased risk of developing ovarian cancer before age 55.
“IGF-1, a mitogenic and anti-apoptotic peptide, has been implicated in the development of several cancers,” Dr. Rudolf Kaaks, of the International Agency for Research on Cancer, Lyon, France, and colleagues note. In a case-control study nested within three prospective cohorts, the team examined the association between IGF-1 concentrations and the risk of ovarian cancer.
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