Oral, long-term isosorbide-5-mononitrate therapy lowers atrial natriuretic peptide levels among patients with left ventricular (LV) dysfunction after acute myocardial infarction, research indicates.
There was also a reduced need for additional diuretics among treated patients. Less LV dilatation was observed in patients with more severe LV dysfunction at baseline, found clinicians at the Department of Cardiology, University Hospital, Lund, Sweden.
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