Bedtime glucose levels should determine whether a bedtime snack is necessary for adults with insulin-dependent diabetes, say Canadian researchers.
Investigators from three hospitals affiliated with McGill University, Montreal, Quebec, recruited 15 adults with type 1 or insulin-dependent diabetes as participants in a randomised, placebo-controlled, cross-over trial to determine the impact of four bedtime snack compositions on nocturnal glycaemic control.
The adults were undergoing intensive insulin management using lispro insulin (recombinant human insulin analogue) before meals and neutral protamine Hagedorn (NPH, insulin) at bedtime. The frequency of hypoglycaemia below 4 mmol/L and morning hyperglycaemia above 10mmol/L was also assessed in their study.
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