There is no evidence isolated choroid plexus cyst in women less than 35 years of age increases risk of trisomy 18, reports a United States study.
Amniocentesis is thus not warranted in these patients, underline doctors from the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School and St Peter’s University Hospital, New Brunswick, and Jersey Shore Medical Center, Monmouth County, New Jersey.
Nevertheless, urge Dr K Demasio and colleagues, new and better methods of screening are needed for women with a low risk for trisomy 18.
To determine incidence of this condition in young women with isolated choroid plexus cyst, researchers analysed prospective trials published between 1990 and 2000 and which reported on the total population screened during the study period, maternal age and pregnancy/neonatal outcomes.
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