Screening heart transplantation patients for depression may help identify those at risk of less favourable post-transplantation outcomes, especially among patients with ischaemic heart disease.
Stephan Zipfel, MD, and colleagues at the University of Heidelberg Medical Hospital, in Heidelberg, Germany, studied the value of preoperative self-reported assessment for depression and anxiety in patients who had undergone heart transplantation.
They divided 152 patients with end-stage heart disease into two groups depending on their type of cardiomyopathy. Fifty-seven of the patients had ischaemic and 95 had dilated cardiomyopathy, the researchers report.
While awaiting heart transplantation, the patients were assessed in a multidimensional longitudinal study and proportional hazard models were computed to test for the influence of psychosocial and somatic factors on outcome. Patient depression and anxiety scores were measured in both groups at baseline and their impact on pre- and postoperative mortality were assessed.







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