Laurie Barclay, MD Aug. 5, 2002
A new method of genetic profiling, described in the Aug. 3 issue of The Lancet, may help predict recurrence in Wilms’ tumors. In 18 patients with favorable histology, comparative expressed sequence hybridization (CESH) showed gene overexpression of chromosome 1q in all those who relapsed but in none of those who remained in remission at three years.
“Many more children [with Wilms’ tumor] could be cured without the risk of long-term side effects of treatment if we could identify at presentation subgroups of those who could safely avoid treatment with cardiotoxic chemotherapy drugs and radiotherapy,” senior author Kathy Pritchard-Jones, from Royal Marsden Hospital NHS Trust in Sutton, England, says in a news release. “Conversely, poor survival of those who relapse might be improved by early treatment intensification.”
תגובות רוצה להצטרף לדיון?
יש להתחבר כדי להגיב.
התחבראין תגובות עדיין. היה הראשון להגיב!