Postmenopausal women who use long term estrogen replacement therapy (ERT) are at greater risk of developing ovarian cancer than are women not using hormone replacement therapy (HRT).
Researchers from the National Cancer Institute in Bethesda, Maryland, United States, followed 44,241 women in this study for approximately 20 years.
“Women who used ERT, particularly for 10 or more years, were at significantly increased risk of ovarian cancer,” they say. “We observed an elevated risk of ovarian cancer among long-term ERT users with hysterectomy and among ERT users without hysterectomy who had switched to estrogen-progestin replacement therapy (EPRT).”
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