A low-fat, high-fiber diet heavy in fruits and vegetables has no impact on PSA levels in men over a four-year period, and does not affect the incidence of prostate cancer, according to a study by researchers at Memorial Sloan-Kettering Cancer Center, the National Cancer Institute, and seven other centers.
The four-year, randomized study examined whether a short-term dietary intervention would impact serum prostate-specific antigen (PSA) levels in men – an important marker for the onset and development of prostate cancer.
Results of previously conducted observational studies have differed on whether a low-fat, high-fiber diet protects against prostate cancer. “This is a rigorous and randomized study that provides valuable data which previously did not exist,” said Moshe Shike, MD, lead author of the study and Director of the Memorial Sloan-Kettering Cancer Prevention Program. “Although this study found no protective effect over four years, it is possible that a healthy dietary pattern sustained over many more years will have an inhibitory effect on prostate
cancer.”
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