Airway hyper-responsiveness and respiratory symptoms might not be due to the presence of house dust mites or endotoxin (LPS) in older, long-term asthmatics. In a study presented this week at the annual meeting of the European Respiratory Society (ERS), Dr.
Dirkje S. Postma, of the Department of Pulmonology at University Hospital, Groningen, The Netherlands said that although dust mites and LPS almost certainly are associated with the onset of airway hyper-responsiveness and respiratory symptoms in children, it is not clear whether this is the case for adults.
To test the hypothesis, Dr. Postma and colleagues at the Groningen Research Institute for Asthma and Chronic Obstructive Pulmonary Disease (COPD) assembled a cohort of 83 asthmatics with a means age 55 years, who had developed asthma as children.
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