Systematically applied daytime respiratory function tests can reliably predict sleep-disordered breathing and recognition of nocturnal respiratory failure can improve, say German researchers.
Sleep disordered breathing is a recognised common complication of respiratory muscle weakness in children and adolescents with neuromuscular disorders. Research has identified many predictors, including recognition of a poor prognosis when nocturnal hypercapnic hypoventilation signals respiratory muscle fatigue. However, researchers from Essen’s University, established a study to identify daytime predictors of sleep disordered breathing at onset, and with nocturnal hypercapnic hypoventilation.
Forty nine children and adolescents with progressive neuromuscular disorders underwent studies with inspirational vital capacity, peak inspiration pressure, arterial blood gases, polysomnography and a 10-item questionnaire. Researchers then prospectively compared daytime respiratory function with polysomnographic variables.
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