Proteins associated with inflammation may help identify different levels of stroke risk in men who have hypertension, Swedish researchers report in today’s rapid access issue of Stroke: Journal of the American Heart Association.
Although hypertension (high blood pressure) is a major risk factor for stroke, many people with the disease don’t have strokes. Even among people with similar blood pressure levels, stroke risk varies considerably.
This led researchers to investigate whether low-grade inflammation could contribute to stroke risk in men with high blood pressure. Inflammation is the process by which the body responds to injury.
The study found that men with systolic blood pressure (the top number in a blood pressure reading) at or above 140 millimeters of mercury (mm Hg) and elevated levels of inflammation-sensitive plasma proteins (ISP) were four times as likely to have a stroke as were men who had normal blood pressure and normal ISP levels. Moreover, the inflammatory proteins predicted stroke risk for 10 or more years.
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