Combination therapy with lofepramine, L-phenylalanine, and vitamin B-12, the so-called “Cari Loder regime,” may slightly reduce disability in patients with multiple sclerosis, according to a report in the September Journal of Neurology, Neurosurgery, and Psychiatry.
Cari Loder espoused this regimen in her 1996 book, the authors explain, but no controlled studies have been reported and data supporting the scientific rationale–a potential increase in noradrenaline levels–is scant.
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