Aug. 8, 2002 Botulinum toxin A (Botox) was safe and effective in the treatment of poststroke spasticity of the fingers and wrist, according to the results of a randomized double-blind trial reported in the Aug. 8 issue of the New England Journal of Medicine.
“This is the first large trial to show that botulinum toxin type A improved function and muscle tone following a stroke,” lead author Allison Brashear, MD, from the Indiana University School of Medicine in Indianapolis, says in a news release.
“A number of studies have demonstrated that botulinum toxin type A decreases muscle rigidity in spastic muscles and one small study has shown functional improvement from this therapy. However, use of the therapy has become common practice so the point of this clinical trial was to assess the effects of one-time treatment on a large, controlled group.” In this two-year study involving 19 medical centers, 126 subjects with some degree of spasticity in their wrist or fingers after a stroke were randomized to treatment with either placebo or with one-time injections of 200 to 240 units of botulinum toxin type A.
e-Med Tools
קצר קולע וממוקד
e-Med סמינרים
אי-מד תחקירים
Medscape Tools
Journal Club
מרכזי מידע ושירות
Facebook
מידע למפרסם
מאגר תרופות
מאגר אנשי המקצוע
אינדקס שימושי
חדשות משה"ב
eMed HealthClub
מחקרים קליניים
השאירו תגובה
רוצה להצטרף לדיון?תרגישו חופשי לתרום!