05/27/2002 By Veronica Rose
Sedative-hypnotics may lead to changes in body temperature but the promotion of sleep appears to vary between agents.
Previous research suggested that there was an association between the sleep-promoting effects of the sedative-hypnotics such as melatonin and temazepam and a fall in core body temperature. In this study, scientists at the Centre for Sleep Research, University of South Australia in Woodville investigated whether alterations in body temperature were a general feature of these drugs.
In addition, melatonin and zopiclone were compared to determine sleep inducing, core and peripheral temperature effects. In a double-blind, crossover design, 12 patients (seven males, five females, average age 20.3 years) were given melatonin (5mg), zopiclone (Imovane (TM); 7.5 mg) or a placebo 14.00 hours.
The had been supine from 08.00 to 21.30 hours, in single, light and temperature controlled rooms .
e-Med Tools
קצר קולע וממוקד
e-Med סמינרים
אי-מד תחקירים
Medscape Tools
Journal Club
מרכזי מידע ושירות
Facebook
מידע למפרסם
מאגר תרופות
מאגר אנשי המקצוע
אינדקס שימושי
חדשות משה"ב
eMed HealthClub
מחקרים קליניים
השאירו תגובה
רוצה להצטרף לדיון?תרגישו חופשי לתרום!