NEW YORK (MedscapeWire) Apr 25 Because antidepressant use during pregnancy is controversial, there have been few treatment options for the 5% of pregnant women who meet criteria for major depression. These women may respond to bright light therapy in the morning, according to results of an open trial published in the April issue of the American Journal of Psychiatry.
"The availability of an easy-to-use, potentially non-toxic antidepressant — light therapy — in pregnancy is a clinically attractive option," lead author Dan A. Oren, MD, from Yale University School of Medicine, in New Haven, Connecticut, told Reuters Health.
For 3 to 5 weeks, 16 pregnant patients with major depression received bright light therapy for 1 hour after awakening in the morning and showed no evidence of adverse effects. On the Hamilton Depression Rating Scale, Seasonal Affective Disorders Version, mean depression ratings improved by 49% after 3 weeks of treatment and by 59% in the 7 patients who had 5 weeks of treatment.
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