Genetic factors far outweigh environmental influences on the development of acne in women, investigators report.
This finding should stimulate a search for genes that might lead to new therapies for the condition, they write. The investigators, at the Medical College of Georgia, Augusta, Georgia, Cancer Research U.K., and St Thomas’ Hospital, in London, England, noted that although clinical experience indicated that acne appeared to run in families, few studies have looked into its genetic basis.
The investigators recruited 458 pairs of monozygotic twins and 1,099 pairs of dizygotic twins, all women, mean age 46 years, to study the relative contribution of genetic and environmental factors on liability to acne.
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