Single photon emission computed tomography (SPECT), which can identify patterns of change in cerebral blood flow during seizures in children with epilepsy, may help direct epilepsy surgery and improve outcomes, researchers in France have found. A. Kaminska, from the department of neuropediatrics, Saint Vincent de Paul Hospital, Paris, France, and colleagues from other French institutions set out to validate the ability of ictal SPECT to localize the epileptiogenic zone in children.
To do so, they determined the topography of the area of increased ictal perfusion in 20 children, aged 10 months to 17 years, subtracting interictal from ictal scan values. They compared these values with intracranial electroencephalogram (EEG) recordings to see which approach provided better postsurgical outcomes.
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