There has been a rise of suspected fatal side effects in the past 10 years in Britain from drugs prescribed to children and reported by doctors to the United Kingdom Medicines Control Agency.
Anti-epileptic drugs were associated with the highest number of reported deaths, in particular liver damage, according to the research by Dr Imti Choonara and colleagues at the Academic Division of Child Health, University of Nottingham, Nottingham.
The suspected fatal side effects were originally reported by doctors to the agency through a voluntary Yellow Card alert. Excluded from the study were reactions to vaccines and overdoses, and the researchers made no attempt to formally assess the cause of a child’s death. They emphasise: “Our study has not looked at evaluating the benefit of medicines, but for all the medicines studied, the overall benefit to children is likely to be far greater than the risk.”
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