Lower urinary tract infections (UTIs) in children can be successfully eradicated with a 2- to 4-day short course of oral antibiotics, authors of a meta-analysis report in the August issue of Archives of Diseases of Childhood.
Dr. Elisah M. Hodson and colleagues from The Children’s Hospital at Westmead, New South Wales, Australia, reviewed the findings from 10 clinical trials involving 652 children with lower tract UTI treated with either short-course oral antibiotics (2 to 4 days) or standard-duration oral antibiotics (7 to 14 days).
There was no significant difference in the frequency of positive urine cultures between the short-course and standard-duration antibiotic therapy 0 to 7 days after treatment and 10 days to 15 months after treatment. There were also no significant between-group differences in the development of resistant organisms or in recurrent UTIs.
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