Coronaviruses Are Low In Neonates, Absent In Children With Community Acquired Infections

06/07/2002
By Veronica Rose

There is a low incidence of nosocomial viral respiratory infections in neonates despite the high rate of community acquired infections among hospitalized children.

French researchers cite human coronaviruses as the most important common pathogen during the study period. Paediatricians at the University Hospital in Brest designed a study to ascertain the incidence of nosocomial viral respiratory infections (NVRI) in neonates and children admitted to paediatric and neonatal intensive care units (PNICU).

They also sought to determine the prevalence of NVRI. The study included 64 neonates (below 28 days old), and 56 children above this age admitted to hospital with community acquired infections between November 1997 and April 1998.

Nasal samples were obtained by cytological brush on admission and weekly. These samples were taken on a monthly basis from staff. The researchers used indirect immunofluorescence to undertake virological studies. Viruses included were Human coronavirus strains 229E and 0C43, respiratory syncytial virus (RSV), influenza virus types A and B, paramyxoviruses 1,2 and 3 and the adenovirus.

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