ECCMID: Infectious Cause for Sudden Infant Death Syndrome?

By Ian Mason
Special to DG News

MILAN, ITALY — April 30, 2002 — Researchers presented evidence of a potential infectious cause for sudden infant death syndrome (SIDS) at the 12th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID).

Their study showed that curlin, a protein produced under certain conditions by the common gut bacteria Escherichia coli, was present in the serum of 68 babies who died of SIDS, but not in any of 60 healthy babies. The researchers chose to investigate E. coli because strains isolated from SIDS babies are more often toxic to cell cultures than strains taken from healthy babies.

Combined with the previous reports that serum from babies who have died of SIDS is toxic to chick embryos, HeLa cells and mice, the findings indicate the presence of a toxin, said Dr. Paul N. Goldwater, MD, of The Women and Children's Hospital, North Adelaide, Australia.

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