Patients with type 2 diabetes may have better blood glucose control and weight loss without adversely affecting their serum lipid levels if they substitute saturated fats for starch in their diets.
Researchers led by J.H. Hays at the Christiana Care Health Services, Inc., in Newark, Delaware in the United States, retrospectively reviewed the medical records of 151 patients with type 2 diabetes, who had completed a one year follow-up after a dietary prescription for a high saturated fat diet with avoidance of starch.
The patients were compared with 132 historical control subjects, who had been allowed unlimited monounsaturated fat and restricted starch. The researchers compared the haemoglobin A1c levels, serum lipid levels, and weight loss or gain among patients in the diet group and historical controls. They also looked for associations between these clinical measurements and other therapy, including metformin, sulfonylurea, insulin, troglitazone, or lipid lowering drugs.
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