NEW YORK (Reuters Health) May 30 –
Chronic leptin treatment leads to improved insulin sensitivity in the liver and in muscle and to reversal of hepatic steatosis in patients with severe lipodystrophy, US investigators report.
Earlier this year, the research team reported that leptin deficiency appears to be the main cause of metabolic abnormalities associated with severe lipodystrophy and that leptin treatment ameliorated these abnormalities in nine patients.
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