NEW YORK (MedscapeWire) May 06
Dietary folate reduces stroke risk by 20%, according to results of a 20-year prospective study reported in the May 3 issue of Stroke. “Our data support the existing recommendation to consume 400 mcg of folate per day,” lead author Lydia A. Bazzano, PhD, from Tulane School of Public Health and Tropical Medicine in New Orleans, Louisiana, says in a news release. “For doctors, this study would suggest that screening patients’ dietary folate intake and promoting the recommended level may decrease patients’ risk of stroke.” This study followed 9764 men and women, aged 25-74 years, without cardiovascular (CV) disease when they enrolled in the National Health and Nutrition Examination Survey I Epidemiologic Follow-up Study (NHEFS). Median folate intake was 203.7 mcg per day, although white men tended to consume more folate. From 1971-1992, subjects had 926 strokes and 3758 CV events. Subjects who consumed at least 300 mcg of folate daily had a 20% lower risk of stroke and a 13% lower risk of CV disease than those consuming less than 136 mcg of folate daily. Subjects with higher folate intake had slightly lower average systolic blood pressure and lower average total cholesterol levels than those who ate less folate.
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