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Polyunsaturated fatty acid supplementation may prevent adult hypertension

מתוך medicontext.co.il

By Steven Reinberg

WESTPORT, CT (Reuters Health) – Supplementing infant and childhood diets with long-chain polyunsaturated fatty acids may prevent hypertension in adulthood, according to Dr. Undurti N. Das from EFA Sciences, LLC, Norwood, Massachusetts.

"Infants who are breastfed for more than 12 months have a very low incidence of hypertension," Dr. Das told Reuters Health.

Dr. Das believes that this protective effect is due to the breast milk's polyunsaturated fatty acid profile, which is rich in docosahexaenoic acids (DHA) and arachidonic acid (AA), according to his report in the September issue of Hypertension: Journal of the American Heart Association.

Likewise, when DHA levels are reduced in animal models, Dr. Das said, the animals develop hypertension as adults. There is also evidence that when these fatty acids are given to adults who have mild to moderate hypertension, blood pressure returns to normal, he added.

Because breastfeeding may not supply all the polyunsaturated fatty acids needed to prevent hypertension, Dr. Das hypotheses that hypertension could be prevented by supplementing the child's diet with long-chain polyunsaturated fatty acids from birth through early childhood.

"Intervention needs to be done early, because once the neural mechanisms involved in the development of hypertension are developed, prevention may be too late," he said.

The researcher recommends that a clinical study be conducted with children who are supplemented with polyunsaturated fatty acids from birth to about 5 years of age and are then followed to see if hypertension develops.

These fatty acids prevent cardiac arrhythmias, type 2 diabetes, and reduce the cholesterol and triglyceride levels, he said. Polyunsaturated fatty acids also reduce the production of harmful cytokines, such as tumor necrosis factor, interleukin 1beta and interleukin 6, Dr. Das added. "Perhaps polyunsaturated fatty acid supplementation should be given lifelong."

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