CNM: No Evidence that ACE Inhibitors, Aspirin Reduce Mortality in Dialysis Patients

By W. A. Thomasson

Special to DG News

CHICAGO, IL — April 22, 2002 — There was no evidence that ACE inhibitors or aspirin reduced overall mortality in dialysis patients, according to analysis of data from a large United States databank on patients with end-stage renal disease.

However, the analysis confirmed that beta-blockers, calcium channel blockers and HMG-CoA reductase inhibitors (statins) did have an effect on mortality, said Fernando Trespalacios, MD, and colleagues at Walter Reed Army Hospital in Washington, DC

They presented their research at the American Kidney Society's Clinical Nephrology meeting.

The study used data from the United States Renal Data System Dialysis Morbidity and Mortality Study Wave II, which includes outcomes through July 1998 of a randomly selected cohort of end-stage renal disease patients who began dialysis treatment in 1996; survival data for these patients are available through March 2000.

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