Eradicating bacterial overgrowth in patients with irritable bowel syndrome (IBS) and small intestinal bacteria overgrowth (SIBO) appears to result in some normalisation of motility, researchers in the United States say.
Patients with IBS with SIBO still present were found to have less frequent phase III small intestinal motility on antroduodenal manometry than IBS patients with eradicated overgrowth. Investigators from Cedars-Sinai Medical Centre in Los Angeles, California, compared 68 consecutive IBS patients with SIBO and 30 controls in a case-control study designed to investigate the role of small intestinal motility. Patients with SIBO were identified by lactulose breath test.
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