WESTPORT, CT (Reuters Health) – Using scanning electron microscopy to individually "fine-tune" hormonal priming of the uterine epithelium prior to in vitro fertilization (IVF) can improve the success rate of frozen embryo transfer.
Drs. Susan M. Adams and Christopher R. Murphy, of the University of Sydney in Australia, describe the procedure, which was performed with a 47-year-old woman who had a history of failed attempts of frozen embryo transfer, in the October 1st issue of BioMed Central (BMC) Pregnancy and Childbirth.
The researchers used data from endometrial biopsy and scanning electron microscopy to ascertain the maturity of the uterine epithelium and its receptiveness to a fertilized embryo. Based on this information, they altered doses of exogenous estrogen and progesterone until the uterine epithelium appeared fully mature and primed for implantation.
"The uterine morphology changed from a hypotrophic to a mature, receptive epithelium such that embryo transfer resulted in the birth of two healthy boys," the investigators write.
Drs. Adams and Murphy believe their success demonstrates the feasibility of using electron microscopy "as a tool, on a case-by-case basis, to evaluate manipulation of the menstrual cycle in patients who have previously failed to achieve implantation with embryo transfer."
BMC Pregnancy Childbirth 2001.
e-Med Tools
קצר קולע וממוקד
e-Med סמינרים
אי-מד תחקירים
Medscape Tools
Journal Club
מרכזי מידע ושירות
Facebook
מידע למפרסם
מאגר תרופות
מאגר אנשי המקצוע
אינדקס שימושי
חדשות משה"ב
eMed HealthClub
מחקרים קליניים
השאירו תגובה
רוצה להצטרף לדיון?תרגישו חופשי לתרום!