Non-rapid eye movement (non-REM) sleep may facilitate seizure activity in patients with epilepsy, according to a cross-sectional study.
Investigators, led by Daniela Minecan from the University of Michigan Medical School, Ann Arbor, United States, reviewed overnight video-electroencephalogram-polysomnographies (VPSGs) collected in their Sleep and Epilepsy Laboratories among 55 patients with epilepsy. Using the VPSG results, the researchers identified 117 seizures.
Overall, 95% of the seizures that the researchers identified occurred during non-REM sleep: 20% in stage 1, 61% in stage 2 and 14% in stages 3 and 4. By adjusting for the amount of time spent in each stage of sleep, the investigators determined that patients had 0.34 seizures per hour in stage 1 of non-REM sleep, 0.38 per hour in stage 2, 0.29 per hour in stage 3 or 4 and 0.09 per hour of REM sleep.
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