In a study of patients with severe, chronic, nonmalignant pain requiring opioid treatment, oral transmucosal fentanyl citrate (OTFC) proved to be effective and safe and permitted an overall reduction in the use of opioids for break-through pain. Many experienced improved quality of life (QOL), as exemplified by increasing mobility, energy and sleep.
Dr. Forest Tennant, of the Veract Intractable Pain Centers in West Covina, California, and associates enrolled 100 consecutive patients who had experienced severe pain for at least 3 years. More than half suffered from degenerative spinal disease. Other common conditions included fibromyalgia, migraine, neuropathies and congenital skeletal disease.
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