The excessive daytime sleepiness seen in about half of people with end-stage renal disease is related both to uraemia and sleep fragmentation associated with periodic leg movement. Dr PJ Hanly and colleagues of the Department of Medicine, St Michael’s Hospital University Health Network, Humber River Regional Hospital, University of Toronto, Ontario, Canada, studied 24 patients who were receiving conventional haemodialysis (CHD).
The aim was to determine the severity and pathogenesis of daytime sleepiness in these patients with end-stage renal disease. The researchers also wanted to evaluate the impact of nocturnal haemodialysis, a new technique that theoretically could improve sleep quality and daytime sleepiness, as it provides better clearance of uraemic toxins than conventional haemodialysis.
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