Appendectomy may protect against inflammatory bowel disease (IBD) with respect to time of onset and severity of disease, according to a study comparing patients with community age-matched controls which was reported in the December issue of Gut.
“Compared with patients without prior appendectomy, appendectomy before diagnosis delays disease onset in ulcerative colitis and Crohn’s disease and gives rise to a milder disease phenotype in ulcerative colitis,” write G. L. Radford-Smith, from Royal Brisbane Hospital in Australia, and colleagues.
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